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Capstar®
Novartis is proud to present its latest product in our all out attack on fleas: Capstar®.
Capstar is a fast acting, safe, non-pesticide way to finally get rid of fleas without exposing your pet (and everyone in the home) to potentially harmful pesticides.
Capstar begins working within 15 minutes to remove all adult fleas on your pet. You will actually see dead fleas falling from your pet.
If you have further questions on Capstar, please ask your veterinarian or you can call Novartis directly at 1-800-387-6325 and ask for technical services.
Features
Only new Capstar provides the fastest flea relief with no pesticide residue.
- Is approved for use with both dogs and cats.
- Capstar Starts working to kill fleas within 15 minutes.
- Labeled safe for puppies and kittens as young as 4 weeks of age and proven safe in pregnant and nursing dogs.
- It is safe enough to give once a day if needed in heavy infestations.
- You will see fleas literally falling off your pet.
- Capstar is not a pesticide and leaves no messy residue so its Hug-Safe!
- Over 90% of fleas are gone within 4 hours.
- Is only available from your veterinarian.
- Comes in two sizes. One for small dogs and cats and one for larger dogs.
- Capstar is safe to use with Program
- Flea detection can be achieved by examining the skin for signs of flea activity by parting the pet's coat.
- It is important to treat all dogs and cats in a household: fleas can reproduce on untreated dogs and cats and allow infestations to persist. Because immature fleas continue to develop into adult fleas for several weeks after the administration of Capstar, repeated treatment may be necessary for optimal control of infestation.
Directions For Use
Capstar (nitenpyram) Tablets have been developed for the oral treatment of flea infestations on cats and dogs. The active ingredient, nitenpyram, is a systemic flea adulticide which rapidly and completely eliminates adult fleas taking a blood meal from a treated animal. Nitenpyram interferes with normal nerve transmission in the fleas and leads to the death of these parasites.
Capstar (nitenpyram) Tablets are indicated for the rapid elimination of fleas (Ctenocephalides felis) on dogs, cats, puppies and kittens four weeks of age and older.
Capstar Tablets are available in two concentrations of nitenpyram for convenient dosing: 11.4 mg per tablet for small dogs and cats and 57 mg per tablet for large dogs. The minimum recommended dosage is 1 mg of nitenpyram per kg of body weight. The product can be given directly into the mouth, or mixed with the pet's favorite food according to the following schedule:
| Weight of Cat | Dose (Tablets) |
|---|---|
| 1 - 11kg | One small (11.4 mg) tablet per day, until fleas are no longer found on the host. |
| 11 - 57kg | One large (57 mg) tablet per day, until fleas are no longer found on the host. |
Note: Effective long-term flea control demands an integrated approach. Monthly administration of an insect development inhibitor, such as lufenuron (Sentinel™, Program®), will prevent the development of immature stages of the flea's life cycle.
Safety
Capstar (nitenpyram) has a wide margin of safety in the intended species when used as per label directions. It can be safely administered to dogs, cats, puppies and kittens four weeks of age and older, pregnant or lactating females and breeding male and female dogs and cats.
Capstar (nitenpyram) Tablets have been administered safely to cats and dogs in conjunction with other commonly used veterinary products including anthelmintics, antibiotics, corticosteroids, vaccines and shampoos.
There are no known contraindications to the use of this product in cats.
Pharmacology
The active ingredient of Capstar, nitenpyram, is a novel molecule belonging to the chemical class of neonicotinoid compounds, which bind with and inhibit insect specific nicotinic acetylcholine receptors; however, it does not inhibit acetylcholinesterase. It interferes with normal nerve transmission and leads to the death of the fleas.
Nitenpyram is very rapidly and almost completely absorbed from the gastrointestinal tract of cats and dogs; feeding does not influence absorption. On average, the maximum blood concentration is reached 1 hour (range: 15 to 90 minutes) after administration in both species, and the elimination half-life is about 3 hours in dogs and 7.5 hours in cats. More than 90% of the active ingredient is eliminated in the urine within one day in dogs and two days in cats, mainly as unchanged nitenpyram.
Nitenpyram starts working rapidly after dosing and kills >98% of the fleas on the pet within 6 hours; all adult fleas are eliminated 24 hours after a single treatment.
CAUTION: Do not administer this product to puppies or kittens less than four weeks of age.
WARNING: Keep this, and all drugs, out of the reach of children; if accidentally swallowed, call a physician.
STORAGE: Do not store above 25°C. Protect from humidity.
Presentation
Capstar Tablets are available in two concentrations of nitenpyram for convenient dosing: 11.4 mg per tablet for small dogs and cats and 57 mg per tablet for large dogs. Each size is offered for sale in aluminum blisters containing six tablets per package.

